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Neisseria meningitis, IgG, Vaccine Response, MAID
Neisseria meningitis, IgG, Vaccine Response, MAID
 
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Description
 

Includes

Serotypes A, C, Y, W-135

Methodology

Multi-Analyte Immunodetection (MAID)

Reference Range(s)

Serogroup A <4.0 mcg/mL
Serogroup C <5.0 mcg/mL
Serogroup Y <4.0 mcg/mL
Serogroup W-135 <3.0 mcg/mL

Clinical Significance

This assay measures serum IgG antibodies recognizing polysaccharide antigens from the four Neisseria meningitidis serogroups included in the licensed meningococcal vaccine. The meningococcal vaccine response is best evaluated by testing pre-vaccination and post-vaccination samples in parallel. A two-fold or greater increase for at least two serogroups is expected when comparing post-vaccination to pre-vaccination results. N. Meningitidis IgG levels peak approximately one month post-vaccination, but decline markedly by two years.


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