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CERULOPLASMIN

 
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Description
 

CPT Code(s)

82390

Methodology

Nephelometry

Limitations

Since ceruloplasmin is an acute phase reactant, caution is necessary when inflammation or infection are present.

Reference Range(s)

AgeMale (mg/dL)Female (mg/dL)
0-30 Days8-253-28
31 Days-11 Months15-4815-43
1-3 Years25-5629-54
4-6 Years29-5626-54
7-9 Years25-5223-48
10-12 Years21-5121-48
13-15 Years20-5021-46
16-18 Years20-4522-50
>18 Years18-3618-53

Clinical Significance

Decreased levels of ceruloplasmin are found in Wilson's Disease, fulminant liver failure, intestinal malabsorption, renal failure resulting in proteinuria, chronic active hepatitis and malnutrition. Elevated levels are found in primary biliary cirrhosis, pregnancy (first trimester), oral contraceptive use and in acute inflammatory conditions since ceruloplasmin is an acute phase reactant.

Alternative Name(s)

Wilson's Disease, Copper Oxide


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