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COPPER, Plasma

 
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Description
 

CPT Code(s)

82525

Methodology

Inductively-Coupled Plasma/Mass Spectrometry (ICP/MS) • Atomic Spectroscopy (AS)

Reference Range(s)

≤5 Months 38-104 mcg/dL
6-11 Months 24-152 mcg/dL
12 Months-23 Months76-193 mcg/dL
1-3 Years87-187 mcg/dL
4-5 Years56-191 mcg/dL
6-9 Years117-181 mcg/dL
10-13 Years87-182 mcg/dL
14-17 Years75-187 mcg/dL
≥18 Years70-175 mcg/dL

Clinical Significance

Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Copper concentrations increase in acute phase reactions and during the third trimester of pregnancy. Copper concentrations are decreased with nephrosis, malabsorption, and malnutrition. Copper concentrations are also useful to monitor patients, especially preterm newborns, on nutritional supplementation. Results of copper are often interpreted together with ceruloplasmin.


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