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IMMUNOGLOBULIN A

 
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Description
 

CPT Code(s)

82784

Methodology

Immunoturbidimetric

Limitations

IgA-deficient individuals may have circulating IgA antibodies that can mediate fatal anaphylactoid reactions if IgA is infused or transfused. The absence IgA antibodies does not necessarily indicate the patient may not suffer anaphalaxis because pre-existing antibodies to other serum proteins may exist and cause anaphalaxis.

Reference Range(s)

Cord Blood1-3mg/dL
1 Month2-43mg/dL
2-5 Months3-66mg/dL
6-9 Months7-66mg/dL
10-12 Months 12-75mg/dL
1-3 Years24-121mg/dL
4-6 Years33-235mg/dL
7-9 Years41-368mg/dL
10-11 Years64-246mg/dL
12-13 Years70-432mg/dL
14-15 Years57-300mg/dL
≥16 Years81-463mg/dL

Clinical Significance

Increased IgA is associated with monoclonal IgA myeloma, respiratory and gastrointestinal infections, and malabsorption; decreased IgA is found in selective IgA deficiency and in ataxia telangiectasia.

Alternative Name(s)

Immunoglobulin A


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