30278
84432,86800
Thyroglobulin, Thyroglobulin AntibodiesClinical Significance
Thyroglobulin (TG) is a secretory product only of the thyroid gland. The major clinical use of serum TG measurement is to monitor, but not to diagnose, patients with well-differentiated thyroid cancers. The measurement of thyroglobulin, after thyroidectomy and ablation of the thyroid gland, is useful to determine metastasis. Deficient TG synthesis is observed in infants with goitrous hypo-thyroidism. Most patients with thyroid autoimmune disease have thyroglobulin antibody. With immunometric assays (sandwich assays), TGAB interference typically produces inappropriately low TG results, most likely caused by endogenous TG immune complexes that block one or more of the reagent antibodies from binding endogenous TG.
TG and ATG,ATG and TG
2 mL serum
1 mL
Serum Separator Tube (SST®)
Room temperature
Room temperature: 7 daysRefrigerated: 7 daysFrozen: 28 days
Gross hemolysis • Gross lipemia
Immunoassay (IA)
Set up: Tues-Sat a.m.; Report available: 2-3 days
See individual tests