CPT Code(s)

86663

Methodology

Immunoassay (IA)

Reference Range(s)

EBV EA-D Ab (IgG)

Clinical Significance

Primary infection by EBV causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders including tumors. IgG recognizing early antigen D typically appears within a month after clinical presentation and is transient, lasting only 3-4 months. Persistently elevated levels suggest reactivation or persistence of EBV infection.