is increased in congestive heart failure, left ventricular hypertrophy,
acute myocardial infarction, coronary angioplasty, and hypertension.
Elevations are also observed in pulmonary hypertension (indicating right
ventricular dysfunction), acute lung injury, hypervolemic states,
chronic renal failure and cirrhosis. Decreasing levels indicate
therapeutic response to anti-hypertensive therapy.