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B Type Natriuretic Peptide (BNP)
B Type Natriuretic Peptide (BNP)
 
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Description
 

Clinical Significance

BNP is increased in congestive heart failure, left ventricular hypertrophy, acute myocardial infarction, coronary angioplasty, and hypertension. Elevations are also observed in pulmonary hypertension (indicating right ventricular dysfunction), acute lung injury, hypervolemic states, chronic renal failure and cirrhosis. Decreasing levels indicate therapeutic response to anti-hypertensive therapy.

BNP is used to diagnose or monitor congestive heart failure (CHF). It is a marker of cardiac dysfunction that correlates with the severity of symptomatic and asymptomatic left ventricular hypertrophy and CHF (including the New York Heart Association classification). BNP can be used to differentiate heart failure from pulmonary dyspnea. If the patient’s values are within the reference interval, then the patient’s symptoms are probably not due to heart failure. Conversely, when the patient’s values exceed the reference interval, there is an increased probability that the patient is in heart failure, and further cardiac assessment is warranted. BNP serves as a guide for management and prognosis. Successful therapy for heart failure typically results in a decrease in BNP concentrations

CPT Code(s)

83880

Methodology

Immunoassay

Reference Range(s)

<100 pg/mL

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