Cortisol, A.M.

CPT Code(s)

82533

Clinical Significance

Cortisol is increased in Cushing's Disease and decreased in Addison's Disease (adrenal insufficiency).

Patient Preparation

Assay is not recommended when patient is receiving prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Collection Instructions

Collect specimen between 7-9 a.m. Indicate the collection time on the specimen container and test requisition.

Transport Container

Serum Separator Tube (SST®)

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 28 days

Methodology

Immunoassay (IA)

Performing Laboratory

Setup Schedule

Set up: Tues-Sat (Day shift, cutoff 9 a.m.); Report available: 3 days

Reference Range(s)