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Epstein Barr Virus - EBV ANTIBODY PANEL

 
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Description
 

CPT Code(s)

86664, 86665 (x2)

Includes

Epstein-Barr Virus VCA Antibody (IgM), Epstein-Barr Virus VCA Antibody (IgG), Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody (IgG)

Methodology

Immunoassay (IA)

Reference Range(s)

Epstein-Barr Virus VCA Antibody (IgM)

≤0.90Negative
0.91-1.09Equivocal
≥1.10Positive
Epstein-Barr Virus VCA Antibody (IgG)
≤0.90Negative
0.91-1.09Equivocal
≥1.10Positive
Epstein-Barr Virus Nuclear Antigen (EBNA ) Antibody (IgG)
≤0.90Negative
0.91-1.09Equivocal
≥1.10Positive

Clinical Significance

Primary infection by EBV causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders including tumors. VCA-IgM is typically detectable at clinical presentation, then declines to undetectable levels within a month in young children and within 3 months in other individuals. VCA-IgG is typically detectable at clinical presentation, and persists for life. EBNA IgG typically appears during convalescence (3-4 months after clinical presentation) and remains detectable for life.

Alternative Name(s)

EBV


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