The aPTT is a screening
test that will detect deficiencies or inhibitors to the intrinsic
(Factors VIII, IX, XI and XII) and common (Factors II, V, X and
fibrinogen) pathway coagulation factors.
Partial Thromboplastin Time, Activated (aPTT)
Photo-optical Clot Detection
impact by therapeutic levels (potential interference depends upon drug
concentration): Warfarin: prolonged; Heparin (UFH or LMWH): prolonged;
Dabigatran or Argatroban (Thrombin Inhibitors): prolonged; Rivaroxaban
or Apixaban (Factor Xa Inhibitors): prolonged.